Cannabigerolic acid

CBGA

Definition - Cannabigerol is the non-acidic form of cannabigerolic acid, the parent molecule from which other cannabinoids are synthesized. Cannabigerol is a minor constituent of cannabis. 

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Therapeutic Effects- CBGA functions kind of like a stem cell in the cannabis plant. CBGA produces effects on anti-proliferative (anti-cancer), anti-bacterial, anti-inflammatory, and analgesic attributes. CBGA the most important of all of cannabis’ chemical compounds, especially given the centrality THC and CBD have taken in today’s discussion of cannabis’ place in our medicine. So here is a refresher on the cannabinoids CBGA is responsible for synthesizing, including two that are not nearly as researched as THC and CBD. 

Tetrahydrocannabinolic acid

Δ9-THC

Definition - THC is the primary chemical responsible for most of the psychoactive effects associated with cannabis. The effects of THC are induced rapidly as the chemical binds to endocannabinoid receptors in the brain, central nervous system and the immune system.

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Therapeutic Effects - THC produces effects on mood, memory, motor coordination, cognitive ability, sensorium, time sense, and self-perception. THC also has the potential to reduce the effects of inflammation created diseases, like rheumatoid arthritis, because it blocks the production of inflammation-producing hormones.

Cannabidiolic acid

CBDA

Definition - CBDa is the acidic precursor to CBD. CBDa is found in either live or raw forms of cannabis, but it isn't until the plant is dried, cut and heated that CBD is created.

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Therapeutic Effects - CBDa works in the EVS as an inhibitor to the COZ-2 enzyme, which gives it the ability to reduce inflammatory activity in the body. Therepeutic benefits include; reducing inflamation, treating nausea and vomiting, helping with psychosis, and helps promote sleep.

Cannabichromenenic Acid

CBCA

Definition - CBC-a is non-psychoactive, unlike THC, and is located in the most abundant levels in tropical marijuana plant strains.

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Therapeutic Effects - CBC acts on CB1 and CB2 receptors in our nervous system. Therapeutic benefits include; anti-inflammatory, anti-depressant, reduce pain caused by nerve damage, analgesic, neuroprotector, anti-bacterial and anti-fungal, reduces acne, gastrointestinal and inflammatory disorders possessing anti-diarrheal properties, inhibits absorption of anandamide which has been linked to reduction of various types of cancer, and the reduction of migranes.

Cannabigerovarinic Acid

CBGVA

Definition - CBGVA is a precursor cannabinoid which undergoes its own series of enzymatic reactions to form a new 'family' of cannabinoids. These molecular transformations take place in response to changes in environment or weather. As the cannabis plant ages, the initial CBGVA in the plant will react to form the new cannabinoids.  Since CBGVA is also one of the produced acids of CBD thus we can say that it might possess similar benefits as that of CBG.

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Therapeutic Effects - CBG has long lasting effects in reducing inflammation to inflammatory bowel disease, Anti-cancer, it can be concluded that CBGVA might also possess similar medicinal benefits.

Tetrahydrocanabivarinic Acid

THCVA

Definition - THCV doesn't begin as cannabigerolic acid unlike THC, CBD, and CBC. CBGVA is broken down to tetrahydrocannabivarin carboxylic acid (THCVA) by the enzyme THCV synthase. At that point, THCVA can be decarboxylated to create THCV.

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Therapeutic Effects - A new potential treatment against obesity-associated glucose intolerance. 

Cannabichromevarinic acid

CBCVA

Definition - CBCV

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Therapeutic Effects - CBCVA targets receptors in the body to help with daily functions such as appetite, sleep patterns, mood, and movement. 

Cannabichromevarin acid

CBCV

Definition - CBCV is a propyl cannabinoid, which differentiates from CBC, CBCV's predecessor and counterpart. Since CBCV is a propyl cannabinoid, this simply means that the molecular structure is different than its predecessor. 

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Therapeutic Effects - CBCV is known specifically to be an extremely effective anticonvulsant.